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Calcium Levofolinate
CAS No. 80433-71-2
Calcium Levofolinate( Calcium levofolinate | CL307782 )
Catalog No. M19124 CAS No. 80433-71-2
Calcium Levofolinate, a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 32 | In Stock |
|
| 100MG | 43 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameCalcium Levofolinate
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NoteResearch use only, not for human use.
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Brief DescriptionCalcium Levofolinate, a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.
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DescriptionCalcium Levofolinate, a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.(In Vivo):Levoleucovorin Calcium (6, 20 or 60 mg/kg/day; i.v.; for 4 weeks) enhances the toxicity of 5-Fluorouracil.
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In Vitro——
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In VivoLevoleucovorin Calcium (6, 20 or 60 mg/kg/day; i.v.; for 4 weeks) enhances the toxicity of 5-Fluorouracil. Animal Model:Crj:CD(SD)BR rats (5 weeks)Dosage:6, 20 or 60 mg/kg/day Administration:i.v.; for 4 weeks (combined with 10 mg/kg/day 5-Fluorouracil)Result:Decreased the RBC counts, increased extramedullary hematopoiesis and enhanced the suppression of lymphatic organs.Induced the potentiation in the toxicity of 5-Fluorouracil appeared to be mainly immuno-suppression and myelosuppression, which were related to the anti-tumor activity of 5-Fluorouracil.
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SynonymsCalcium levofolinate | CL307782
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number80433-71-2
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Formula Weight511.5
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Molecular FormulaC20H21N7O7·Ca
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Purity>98% (HPLC)
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SolubilityH2O : 26.5 mg/mL 51.81 mM
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SMILESC(=O)([C@@H](NC(=O)c1ccc(cc1)NC[C@@H]1N(c2c(=O)nc([nH]c2NC1)N)C=O)CCC(=O)[O-])[O-].[Ca+2]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Lebitasy M, Hecq JD, Athanassopoulos A, Vanbeckbergen D, Jamart J, Galanti L.J Clin Pharm Ther. 2009 Aug;34(4):423-8.
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